Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8603658 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL8601825 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL8604865 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL8601243 | 0.78 | — | — | |
| SCHEMBL8603018 | 0.69 | — | — | |
| SCHEMBL8604162 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL376344 | 0.66 | — | — | |
| SCHEMBL9550604 | 0.65 | GPR3 (0.34) | — | |
| SCHEMBL8603108 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL3192369 | 0.62 | GPR3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544308-B1 | Novel metallocene and process for producing polyolefin using the same | SHOWA DENKO KK (JP) | 1998-02-18 | — | — | EP | disclosed |
| US-5349032-A | Metallocene and process for producing polyolefin using the same | SHOWA DENKO K.K. (JP) | 1994-09-20 | — | — | US | disclosed |
| US-5329031-A | Metallocene and process for producing polyolefin using the same | SHOWA DENKO K.K. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0544308-A1 | Novel metallocene and process for producing polyolefin using the same | SHOWA DENKO KABUSHIKIKAISHA (JP) | 1993-06-02 | — | — | EP | disclosed |