SCHEMBL8604698

SCHEMBL8604698

CS(=O)(=O)Nc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.66
SMN1; SMN2 Q16637 4/20 0.66
L3MBTL1 Q9Y468 4/20 0.66
MAPK1 P28482 4/20 0.66
EGFR P00533 3/20 0.66
TDP1 Q9NUW8 2/20 0.66
PABPC1 P11940 1/20 0.66
RAB9A P51151 1/20 0.66
PGAM1 P18669 1/20 0.60
MAOA P21397 1/20 0.58
ALDH1A1 P00352 5/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
LMNA P02545 4/20 0.52
KDM4E B2RXH2 1/20 0.52
KEAP1 Q14145 2/20 0.51
NFE2L2 Q16236 1/20 0.49
HTT P42858 2/20 0.48
POLB P06746 2/20 0.48
RAD52 P43351 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348415 0.83 MAPT (0.62) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL9348518 0.83 MAPT (0.62) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL10588513 0.82 MAPT (0.61) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL13564131 0.82 PGAM1 (0.56) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL12006228 0.82 MAPT (0.61) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL29361322 0.79 MAPT (1.00) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL1050030 0.79 MAPT (1.00) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL8605499 0.79 LMNA (0.65) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL9348365 0.79 MAPT (0.57) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR
SCHEMBL11167085 0.79 MAPT (0.71) MAPTSMN1; SMN2L3MBTL1MAPK1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826739-A1 Process for the preparation of substituted aminoanthraquinones BAYER AG (DE) 1998-03-04 EP claimed
JP-61010549-A None JP disclosed
EP-0826739-A1 Process for the preparation of substituted aminoanthraquinones BAYER AG (DE) 1998-03-04 EP disclosed
EP-0409637-B1 Thermal transfer imaging using sulfonylamino-anthraquinone dyes MINNESOTA MINING & MFG (US) 1995-06-21 EP disclosed
EP-0368750-B1 Process for preparing substituted aminoanthraquinones SUMITOMO CHEMICAL CO (JP) 1994-10-26 EP disclosed
US-5017713-A Alkylation SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1991-05-21 US disclosed
EP-0409637-A1 Thermal transfer imaging using sulfonylamino-anthraquinone dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-23 EP disclosed
EP-0368750-A2 Process for preparing substituted aminoanthraquinones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed
JP-S6110549-A SULFONAMIDE MITSUI PETROCHEM IND LTD 1986-01-18 JP disclosed