Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | HTT | P42858 | 4/20 | 0.72 |
| ▸ | HBB | P68871 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC25A5 | P05141 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451081 | 0.84 | MAPT (1.00) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL7145735 | 0.78 | MAPT (0.72) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL6958511 | 0.78 | MAPT (1.00) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL4811658 | 0.78 | MAPT (0.72) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL8856814 | 0.75 | MAPT (0.49) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL6970354 | 0.74 | MAPT (0.68) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL8856821 | 0.71 | ALDH1A1 (0.55) | MAPTHTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22802233 | 0.70 | MAPT (0.61) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL6863960 | 0.70 | HTT (0.66) | MAPTHTTHBBALOX15CYP1A2 | |
| SCHEMBL29603379 | 0.70 | MAPT (0.61) | MAPTHTTHBBALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | claimed |