Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HBB | P68871 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145735 | 0.81 | MAPT (0.72) | HTTMAPTHBBALOX15RAB9A | |
| SCHEMBL22802233 | 0.80 | MAPT (0.61) | HTTMAPTHBBALOX15RAB9A | |
| SCHEMBL29603379 | 0.80 | MAPT (0.61) | HTTMAPTHBBALOX15RAB9A | |
| SCHEMBL11451081 | 0.80 | MAPT (1.00) | HTTMAPTHBBALOX15RAB9A | |
| SCHEMBL9421592 | 0.72 | ALDH1A1 (0.45) | HTTMAPTHBBALOX15RAB9A | |
| SCHEMBL17398601 | 0.72 | NPSR1 (0.66) | RAB9AALDH1A1PARP1NPSR1L3MBTL1 | |
| SCHEMBL9711809 | 0.71 | PARP1 (0.42) | RAB9ALMNAPARP1NPSR1L3MBTL1 | |
| SCHEMBL6958511 | 0.70 | MAPT (1.00) | HTTMAPTHBBALOX15RAB9A | |
| SCHEMBL4811658 | 0.70 | MAPT (0.72) | HTTMAPTHBBALOX15RAB9A | |
| SCHEMBL8604882 | 0.70 | MAPT (0.72) | HTTMAPTHBBALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809206-B2 | CONTACTING A PHENYL ESTER COMPOUND WITH A CYCLIC COMPOUND IN THE PRESENCE OF A SOURCE OF CYANIDE OR FLUORIDE TO PREPARE ACYLATED CYCLIC 1,3-DICARBONYL COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-10-26 | — | — | US | disclosed |
| US-20030232984-A1 | Method for acylating cyclic compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-18 | — | — | US | disclosed |
| US-20020049317-A1 | Method for acylating cyclic compounds | E.I. DU PONT DE NEMOURS AND COMPANY | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049317-A1 | Method for acylating cyclic compounds | LCAT, ACOT7, AGPAT5 | HTT 1452/4885MAPT 4261/4885HBB 4001/4885 |
| US-20030232984-A1 | Method for acylating cyclic compounds | LCAT, ACOT7, AGPAT5 | HTT 1452/4885MAPT 4261/4885HBB 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.