Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055148 | 0.81 | MAPT (0.52) | CYP3A4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29007602 | 0.74 | RAB9A (0.53) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30397064 | 0.74 | MEN1 (0.53) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL29007584 | 0.74 | GAA (0.46) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL18328075 | 0.71 | MEN1 (0.44) | CYP3A4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29007581 | 0.67 | MEN1 (0.47) | CYP2C19MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30396376 | 0.67 | MEN1 (0.47) | CYP2C19MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30396872 | 0.67 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL1000044 | 0.66 | POLB (0.48) | CYP3A4CYP2C19ALDH1A1POLB | |
| SCHEMBL17221757 | 0.64 | MEN1 (0.41) | CYP3A4MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | claimed |