Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647104 | 0.88 | ADRB2 (0.46) | KMT2AMEN1SLC6A4ALDH1A1MAPT | |
| SCHEMBL957779 | 0.88 | ADRB2 (0.46) | KMT2AMEN1SLC6A4ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL19362148 | 0.86 | ADRB2 (0.45) | KMT2AMEN1SLC6A4ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL4934770 | 0.86 | ADRB2 (0.45) | KMT2AMEN1SLC6A4ALDH1A1MAPT | |
| SCHEMBL756549 | 0.82 | ADRB2 (0.42) | KMT2AMEN1SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL184737 | 0.78 | ROCK1 (0.47) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL3831819 | 0.77 | ALDH1A1 (0.44) | KMT2AMEN1SLC6A4ALDH1A1MAPT | |
| SCHEMBL4380562 | 0.74 | SOS1 (0.46) | KMT2AMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL16649847 | 0.74 | SOS1 (0.46) | KMT2AMEN1ALDH1A1MAPTALOX15 | |
| Methylamine SCHEMBL28014346 | 0.73 | ALDH1A1 (0.46) | KMT2AMEN1SLC6A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723489-A | ADRENERGIC BLOCKING AGENTS OR STIMULANTS FOR GASTROINTESTINAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| US-5541204-A | Aryloxypropanolamine β 3 adrenergic agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0714883-A1 | Aryloxypropanolamine beta 3 adrenergic agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |