Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 6/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | IL1B | P01584 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554751 | 0.89 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DASH1L | |
| Hydrochloric Acid SCHEMBL8605205 | 0.88 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DASH1L | |
| SCHEMBL1554432 | 0.86 | CNR2 (0.46) | PDE4APDE4BPDE4CPDE4DASH1L | |
| SCHEMBL1554082 | 0.80 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7402578 | 0.76 | HDAC3 (0.47) | PDE4APDE4BPDE4CPDE4DHTR3A | |
| SCHEMBL7402575 | 0.73 | HTR3A (0.38) | PDE4APDE4BPDE4CPDE4DASH1L | |
| SCHEMBL8669588 | 0.72 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DASH1L | |
| SCHEMBL1552979 | 0.72 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DSCN5A | |
| SCHEMBL14547319 | 0.71 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DSCN5A | |
| SCHEMBL1554355 | 0.71 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |