Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554432 | 0.77 | CNR2 (0.46) | HTR3APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7402578 | 0.75 | HDAC3 (0.47) | HTR3APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1554751 | 0.74 | PDE4A (0.45) | HTR3APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8605201 | 0.73 | PDE4A (0.47) | HTR3APDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8605205 | 0.73 | PDE4A (0.44) | HTR3APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7397635 | 0.67 | SLC6A3 (0.44) | ALDH1A1 | |
| SCHEMBL1554082 | 0.66 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6155017 | 0.66 | LMNA (0.54) | GAANPSR1 | |
| SCHEMBL1553385 | 0.65 | SLC22A12 (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1555420 | 0.65 | PTGER4 (0.37) | ALDH1A1HTTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934307-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997048697-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1997-12-24 | — | — | WO | disclosed |