Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 10/20 | 0.41 |
| ▸ | CTSK | P43235 | 7/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579767 | 0.88 | NAMPT (0.46) | CTSSCTSKNAMPTCA1 | |
| SCHEMBL8575481 | 0.86 | GLS (0.48) | KDM4ACTSSCTSKNAMPTCTSL | |
| SCHEMBL30159605 | 0.81 | KCNA5 (0.56) | KCNA5KDM4ACTSSCTSKNAMPT | |
| SCHEMBL8018113 | 0.81 | KCNA5 (0.56) | KCNA5KDM4ACTSSCTSKNAMPT | |
| SCHEMBL6186560 | 0.80 | NAMPT (0.52) | NAMPTHDAC6 | |
| SCHEMBL6320846 | 0.79 | KCNA5 (0.51) | KCNA5KDM4ACTSSCTSKNAMPT | |
| SCHEMBL6187094 | 0.79 | TDP1 (0.44) | CTSSCTSKCTSLCTSBIDO1 | |
| SCHEMBL8579008 | 0.78 | AURKA (0.46) | CTSSCTSKNAMPTCTSLCTSB | |
| SCHEMBL6187053 | 0.78 | BRD4 (0.45) | CTSSCTSKNAMPTCTSBCA1 | |
| SCHEMBL5855817 | 0.77 | KCNA5 (0.48) | KCNA5KDM4ACTSSCTSKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998014449-A1 | FUSED PYRAZOLE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1998-04-09 | — | — | WO | disclosed |