Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454997 | 0.86 | SCN4A (0.50) | SCN4ATSHRHTR2AHTR2BLMNA | |
| SCHEMBL325648 | 0.86 | SCN4A (0.60) | SCN4AGAAALDH1A1TSHRHTR2A | |
| SCHEMBL8683353 | 0.84 | SMN1; SMN2 (0.51) | SCN4ATSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL8683356 | 0.84 | SMN1; SMN2 (0.51) | SCN4ATSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL20611234 | 0.82 | SCN4A (0.50) | SCN4AGAAALDH1A1TSHRHTR2A | |
| SCHEMBL14578182 | 0.81 | PTGER1 (0.48) | SCN4AGAAALDH1A1HTR2ACYP1A2 | |
| SCHEMBL16454999 | 0.79 | SCN4A (0.47) | SCN4AGAAALDH1A1TSHRHTR2A | |
| SCHEMBL773261 | 0.79 | ALOX15 (0.59) | SCN4AGAAALDH1A1TSHRHTR2A | |
| SCHEMBL25586015 | 0.78 | SCN4A (0.55) | SCN4AGAAALDH1A1TSHRHTR2A | |
| SCHEMBL16454995 | 0.78 | KDM4E (0.54) | SCN4AALDH1A1TSHRHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
| CN-1078204-C | Amino acid amide derivative, agrohorticultural bactericide, and production process | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2002-01-23 | — | — | CN | disclosed |
| US-5811424-A | CONTROL OF DOWNY MILDEW, LATE BLIGHT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5723469-A | Amino-acid amide derivatives, agricultural or horticultural fungicides, and method for producing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0648740-B1 | AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5574064-A | Amino-acid amide derivatives, agricultural or horticultural fungicides, and method for producing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| CN-1108863-A | Amino acid amide derivative, agrohorticultural bactericide, and production process | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1995-09-20 | — | — | CN | disclosed |
| EP-0648740-A1 | AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | SCN4A 725/4885GAA 630/4885ALDH1A1 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.