SCHEMBL8606264

SCHEMBL8606264

Cc1c(CC(=O)NC(C)CN)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.32
NR5A1 Q13285 1/20 0.32
ALPL P05186 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTR1D P28221 1/20 0.31
HTR1B P28222 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KCNJ6 P48051 1/20 0.30
KCNJ5 P48544 1/20 0.30
KCNJ3 P48549 1/20 0.30
POLB P06746 1/20 0.30
CACNA1I Q9P0X4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8606502 0.87 NR5A2 (0.39) NR5A2NR5A1GAAHTTTSHR
SCHEMBL8608862 0.82 GAA (0.36) NR5A2NR5A1GAAALDH1A1POLB
SCHEMBL8606920 0.80 ALDH1A1 (0.34) HTTL3MBTL1TSHRALDH1A1CACNA1I
SCHEMBL8606266 0.80 HPGD (0.34) NR5A2NR5A1HPGD
SCHEMBL8606817 0.77 HSPA5 (0.50) GAAALDH1A1POLB
SCHEMBL8606269 0.77 NR5A2 (0.41) NR5A2NR5A1HPGDALDH1A1
SCHEMBL8606273 0.75 HTR1D (0.34) NR5A2NR5A1GAAHTTHPGD
SCHEMBL8604378 0.74 HSPA5 (0.35)
SCHEMBL8606831 0.73 GAA (0.50) GAAHTTTSHRALDH1A1POLB
SCHEMBL8607704 0.73 CA2 (0.41) ALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed