SCHEMBL8606644

SCHEMBL8606644

C=C(CCOC(=O)/C=C/c1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 7/20 0.61
AKR1B1 P15121 7/20 0.61
LMNA P02545 2/20 0.56
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
MAOB P27338 1/20 0.52
ALDH1A1 P00352 3/20 0.52
APP P05067 2/20 0.52
CA12 O43570 2/20 0.49
CA4 P22748 2/20 0.49
CA6 P23280 2/20 0.49
CA5A P35218 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
CA5B Q9Y2D0 2/20 0.49
RAB9A P51151 2/20 0.47
CYP3A4 P08684 2/20 0.46
ALOX15 P16050 2/20 0.46
ALOX12 P18054 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10350517 1.00 AKR1B10 (0.61) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL1416438 0.91 AKR1B10 (0.58) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL10351301 0.85 AKR1B10 (0.61) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL29048483 0.84 LMNA (0.59) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL29048484 0.84 LMNA (0.59) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL12520722 0.84 AKR1B10 (0.69) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL9277968 0.84 AKR1B10 (0.83) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL16234738 0.84 AKR1B10 (0.83) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL19279512 0.84 AKR1B10 (0.83) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL9233441 0.82 AKR1B10 (0.48) AKR1B10AKR1B1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850018-B1 ANTIMICROBIAL CONTACT LENSES KERAMED INC (US) 2023-08-23 EP claimed
CN-108478798-B Preparation method of micro-hydrogel capable of loading and slowly releasing hydrophilic and hydrophobic drugs simultaneously 浙江大学 2020-02-14 CN claimed
EP-0179921-B1 BASE MATERIAL HAVING A DYED SURFACE FILM AND DYEING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-08-08 EP claimed
CN-108478798-B Preparation method of micro-hydrogel capable of loading and slowly releasing hydrophilic and hydrophobic drugs simultaneously 浙江大学 2020-02-14 CN disclosed
EP-0830634-A1 LIQUID CRYSTAL ALIGNMENT MATERIALS AND DEVICES The Secretary of State for Defence in Her Britannic Majesty's Government of The United Kingdom of Great Britain and Northern I (GB) 1998-03-25 EP disclosed
WO-1997038349-A1 LIQUID CRYSTAL ALIGNMENT MATERIALS AND DEVICES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1997-10-16 WO disclosed
US-4591544-A Metal image forming materials with light sensitive resin layer and oblique angle deposited metal underlayer KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-05-27 US disclosed
US-4411983-A REMOVAL OF NON-IMAGE AREA WITH WATER MISCIBILITY ORGANIC SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1983-10-25 US disclosed
EP-0082588-A2 Photolithographic elements for the production of metal images KONICA CORPORATION (JP) 1983-06-29 EP disclosed