Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.39 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081658 | 0.86 | CXCR4 (0.51) | CXCR4IL23R | |
| SCHEMBL31255673 | 0.78 | CXCR4 (0.55) | CXCR4IL23R | |
| SCHEMBL30751614 | 0.77 | ACE (0.47) | ACE | |
| SCHEMBL30148151 | 0.76 | ACE (0.45) | CXCR4OPRD1OPRM1ACENTSR2 | |
| SCHEMBL31127567 | 0.76 | OPRK1 (0.48) | OPRD1ACENTSR2NTSR1 | |
| SCHEMBL31127570 | 0.76 | OPRK1 (0.49) | ACENTSR2NTSR1 | |
| SCHEMBL30631705 | 0.75 | CD4 (0.46) | OPRD1ACE | |
| SCHEMBL30880891 | 0.75 | NTSR1 (0.48) | OPRD1NTSR2NTSR1 | |
| SCHEMBL30116344 | 0.74 | ACE (0.47) | OPRD1OPRM1ACENTSR2NTSR1 | |
| SCHEMBL30751582 | 0.74 | ACE (0.44) | ACENTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828521-A1 | SEQUESTERED IMAGING AGENTS | RESOLUTION PHARMACEUTICALS INC. (CA) | 1998-03-18 | — | — | EP | claimed |
| WO-1996038185-A1 | SEQUESTERED IMAGING AGENTS | RESOLUTION PHARMACEUTICALS INC. (CA) | 1996-12-05 | — | — | WO | claimed |