Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063742 | 0.89 | GAA (0.58) | HSP90AA1HSP90AB1NR1H4HSD17B10GAA | |
| SCHEMBL8608126 | 0.84 | LMNA (0.45) | HSD17B10GAAKMT2AALDH1A1LMNA | |
| SCHEMBL8606761 | 0.83 | NR1H4 (0.49) | NR1H4KMT2AKDM4ERARBRARG | |
| SCHEMBL18587755 | 0.81 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1NR1H4HSD17B10GAA | |
| SCHEMBL8608377 | 0.80 | TERT (0.52) | HSP90AA1HSP90AB1NR1H4KMT2AKDM4E | |
| SCHEMBL8607170 | 0.80 | CYP1A2 (0.41) | HSD17B10GAAKMT2AKDM4EESRRG | |
| SCHEMBL8608144 | 0.78 | HPGD (0.43) | HPGD | |
| SCHEMBL7942288 | 0.78 | HPGD (0.53) | HSP90AA1HSP90AB1HSD17B10KDM4EHPGD | |
| SCHEMBL8608296 | 0.78 | TNFRSF1A (0.41) | NR1H4HSD17B10GAAKMT2AKDM4E | |
| SCHEMBL8606900 | 0.78 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1NR1H4HSD17B10RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847187-A | Organic phosphorous compound, a process for producing the same and a use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-08 | — | — | US | disclosed |