Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 3/20 | 0.36 |
| ▸ | PGK2 | P07205 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.31 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.31 |
| ▸ | INPP5B | P32019 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379784 | 0.78 | CA2 (0.53) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL11302336 | 0.78 | CA2 (0.42) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL31193662 | 0.70 | CA2 (0.52) | CA2CA4CA5AALDH1A1FDPS | |
| SCHEMBL3001998 | 0.70 | CA2 (0.52) | CA2CA4CA5AALDH1A1FDPS | |
| SCHEMBL6262029 | 0.69 | CA2 (0.65) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL20379768 | 0.67 | CA2 (0.42) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL31130721 | 0.67 | CA2 (0.42) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL20379773 | 0.67 | MMP1 (0.33) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL20379839 | 0.67 | CA2 (0.42) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL20379807 | 0.67 | CA2 (0.42) | CA2CA4CA5APGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716964-A | BRAIN DISORDERS; ANTIISCHEMIC AGENTS | G.D. SEARLE & CO. (US) | 1998-02-10 | — | — | US | disclosed |