SCHEMBL8607159

SCHEMBL8607159

COc1c(C(C)(C)C)cc(CCC(=O)NCCCN)cc1C(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.54
GAA P10253 4/20 0.54
POLB P06746 1/20 0.48
MEN1 O00255 4/20 0.47
GSK3B P49841 2/20 0.44
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8606674 0.93 KMT2A (0.50) KMT2AGAAPOLBMEN1GSK3B
SCHEMBL8608399 0.92 KMT2A (0.56) KMT2AGAAPOLBMEN1GSK3B
SCHEMBL8608657 0.87 LMNA (0.42) KMT2AGAAMEN1LMNA
SCHEMBL1720422 0.86 GAA (0.73) KMT2AGAAMEN1GSK3BLMNA
SCHEMBL8608212 0.85 KMT2A (0.52) KMT2AGAAPOLBMEN1GSK3B
SCHEMBL8606270 0.84 KMT2A (0.53) KMT2AGAAPOLBMEN1GSK3B
SCHEMBL8607341 0.83 KMT2A (0.39) KMT2AGAAPOLBMEN1GSK3B
SCHEMBL8609737 0.82 KMT2A (0.38) KMT2AGAAPOLBMEN1GSK3B
SCHEMBL8634578 0.81 GAA (0.63) KMT2AGAAMEN1GSK3BLMNA
SCHEMBL1720307 0.81 GAA (0.70) KMT2AGAAMEN1GSK3BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed