SCHEMBL8608657

SCHEMBL8608657

COc1c(C(C)(C)C)cc(CC(=O)NCCCN)cc1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
PTK2 Q05397 1/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8606958 0.93 LMNA (0.39) LMNAL3MBTL1PTK2
SCHEMBL8607172 0.92 LMNA (0.44) LMNAKMT2AGAAMEN1
SCHEMBL8607159 0.87 KMT2A (0.54) LMNAKMT2AGAAMEN1
SCHEMBL8606840 0.85 GAA (0.53) LMNAKMT2AGAAMEN1
SCHEMBL8608114 0.85 LMNA (0.41) LMNAKMT2AGAAMEN1
SCHEMBL8604382 0.83 CA12 (0.37)
SCHEMBL8608298 0.81 MEN1 (0.54) KMT2AMEN1
SCHEMBL8606674 0.81 KMT2A (0.50) LMNAKMT2AGAAMEN1
SCHEMBL8606925 0.81 CA12 (0.36)
SCHEMBL8608401 0.81 GAA (0.46) KMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed