Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608128 | 0.91 | ALOX5 (0.45) | EGFRALOX5PTGS1PTGS2SYK | |
| SCHEMBL8606893 | 0.82 | TNFRSF1A (0.40) | LMNAGAAALDH1A1TNFRSF1ASMN1; SMN2 | |
| SCHEMBL8335744 | 0.80 | GAA (0.50) | CYP1A2CYP2C9CYP2C19ALOX5PTGS1 | |
| SCHEMBL8608299 | 0.78 | TNFRSF1A (0.46) | GAAALDH1A1TNFRSF1ASMN1; SMN2HTT | |
| SCHEMBL8606908 | 0.78 | HSP90AA1 (0.48) | CYP2C9LMNAALDH1A1TYRHTT | |
| SCHEMBL30924511 | 0.78 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19EGFRALOX5 | |
| SCHEMBL8608141 | 0.77 | SMN1; SMN2 (0.47) | CYP1A2CYP2C9CYP2C19EGFRPTGS1 | |
| SCHEMBL8608403 | 0.77 | GAA (0.44) | CYP1A2CYP2C9CYP2C19EGFRLMNA | |
| SCHEMBL8605774 | 0.75 | GAA (0.35) | CYP1A2CYP2C9CYP2C19EGFRALOX5 | |
| SCHEMBL8634581 | 0.75 | GAA (0.58) | CYP1A2CYP2C9CYP2C19LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847187-A | Organic phosphorous compound, a process for producing the same and a use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-08 | — | — | US | disclosed |