Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606893 | 0.92 | TNFRSF1A (0.40) | TNFRSF1AALDH1A1ALOX12KDM4EGAA | |
| SCHEMBL8608128 | 0.83 | ALOX5 (0.45) | TNFRSF1AALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL8606767 | 0.82 | RARA (0.50) | ALDH1A1ALOX12KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8607395 | 0.81 | TNFRSF1A (0.37) | TNFRSF1AALDH1A1SMN1; SMN2SCN5ASCN2A | |
| SCHEMBL8608659 | 0.79 | TNFRSF1A (0.38) | TNFRSF1AALDH1A1KDM4EGAAMAPT | |
| SCHEMBL8608434 | 0.79 | TNFRSF1A (0.36) | TNFRSF1AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8607178 | 0.78 | CYP1A2 (0.44) | TNFRSF1AALDH1A1KDM4EGAAMAPT | |
| SCHEMBL8606928 | 0.78 | TNFRSF1A (0.37) | TNFRSF1AALDH1A1ALOX12KCNH2 | |
| SCHEMBL3579165 | 0.77 | TNFRSF1A (0.51) | TNFRSF1AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8607163 | 0.77 | GAA (0.49) | TNFRSF1AALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847187-A | Organic phosphorous compound, a process for producing the same and a use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-08 | — | — | US | disclosed |