Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607268 | 1.00 | TRPA1 (0.50) | TRPA1CTSSCTSKPSENENCA2 | |
| SCHEMBL8756610 | 0.82 | TRPA1 (0.53) | TRPA1CTSSCTSKCA2 | |
| SCHEMBL8607265 | 0.80 | TRPA1 (0.50) | TRPA1CTSSCTSKCA2 | |
| SCHEMBL22312263 | 0.77 | CTSS (0.43) | TRPA1CTSSCTSKCA2 | |
| SCHEMBL8971989 | 0.77 | TRPA1 (0.57) | TRPA1CTSSCTSKCA2 | |
| SCHEMBL18130613 | 0.76 | AAK1 (0.41) | TRPA1CA2 | |
| SCHEMBL24049442 | 0.74 | PSMB5 (0.55) | TRPA1CTSSCTSKPSENENCA2 | |
| SCHEMBL10175868 | 0.73 | PSENEN (0.58) | TRPA1CTSSCTSKPSENENCA2 | |
| SCHEMBL19089931 | 0.73 | PSENEN (0.58) | TRPA1CTSSCTSKPSENENCA2 | |
| SCHEMBL16667761 | 0.73 | PSENEN (0.58) | TRPA1CTSSCTSKPSENENCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811424-A | CONTROL OF DOWNY MILDEW, LATE BLIGHT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5723469-A | Amino-acid amide derivatives, agricultural or horticultural fungicides, and method for producing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0648740-B1 | AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5574064-A | Amino-acid amide derivatives, agricultural or horticultural fungicides, and method for producing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0648740-A1 | AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |