SCHEMBL8607333

SCHEMBL8607333

C=CNC(=O)C(=C)N1CCCC1=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.32
MITF O75030 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
POLB P06746 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28422680 0.81 LMNA (0.48) LMNAKDM4EMEN1CYP1A2CYP2D6
SCHEMBL10885221 0.75 LMNA (0.42) LMNAKDM4EMEN1CYP1A2CYP2D6
SCHEMBL6650320 0.74 LMNA (0.53) LMNAKDM4EMEN1CYP1A2CYP2D6
SCHEMBL4372909 0.74 TSHR (0.51) LMNACYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL27361301 0.73 LMNA (0.44) LMNAKDM4EMEN1CYP1A2CYP2D6
Ethylene SCHEMBL28313751 0.73 TSHR (0.50) LMNACYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL13792789 0.73 LMNA (0.52) LMNAKDM4EMEN1CYP1A2CYP2D6
SCHEMBL6648950 0.72 LMNA (0.47) LMNAKDM4EMEN1CYP1A2CYP2D6
SCHEMBL346131 0.71 LMNA (0.53) LMNAKDM4EMEN1CYP1A2CYP2D6
SCHEMBL2537024 0.71 LMNA (0.48) LMNAKDM4EMEN1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213594-B1 POLYMERFLOOD PROCESS PHILLIPS PETROLEUM COMPANY (US) 1992-04-22 EP claimed
EP-0176481-B1 UNSATURATED POLYSILOXANES, POLYMERIZABLE COMPOSITIONS AND CONTACT LENSES THEREFROM CIBA-GEIGY AG (CH) 1991-12-11 EP claimed
EP-0176481-A2 Unsaturated polysiloxanes, polymerizable compositions and contact lenses therefrom CIBA-GEIGY AG (CH) 1986-04-02 EP claimed
CN-121085578-A Composite polycarboxylate superplasticizer and preparation process thereof 浙江五龙新材股份有限公司 2025-12-09 CN disclosed
EP-0830407-A1 KREBS CYCLE ACID POLYESTERS AND USE THEREOF DYNAGEN, INC. (US) 1998-03-25 EP disclosed
WO-1996040814-A1 KREBS CYCLE ACID POLYESTERS AND USE THEREOF DYNAGEN, INC. (US) 1996-12-19 WO disclosed