SCHEMBL10885221

SCHEMBL10885221

C=CNC(=O)N1CCCCCC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
MITF O75030 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 2/20 0.35
TP53 P04637 2/20 0.35
STAT6 P42226 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 3/20 0.33
KMT2A Q03164 2/20 0.33
ITGB1 P05556 1/20 0.33
ITGA4 P13612 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
THRB P10828 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28422680 0.93 LMNA (0.48) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL225114 0.77 LMNA (0.46) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL12599179 0.77 MITF (0.46) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL13085727 0.77 MITF (0.46) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL224075 0.77 LMNA (0.46) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL8607333 0.75 LMNA (0.44) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL16439193 0.74 LMNA (0.47) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL14967537 0.74 LMNA (0.47) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL27344164 0.74 LMNA (0.47) LMNAMITFSMN1; SMN2MAPTTP53
SCHEMBL4362204 0.74 LMNA (0.47) LMNAMITFSMN1; SMN2MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103376-A Optical fiber coated with non-radiation curable acrylic hard-soft block copolymer 康宁股份有限公司 2016-11-09 CN disclosed
CN-105722883-A FIBER COATINGS WITH LOW YOUNG'S MODULUS AND HIGH TEAR STRENGTH 康宁股份有限公司 2016-06-29 CN disclosed
EP-0106128-B1 ENAMEL BINDERS INCLUDING BLOCKED ISOCYANATE GROUPS, AND THEIR USE IN CATHODIC ELECTRODEPOSITION BASF Aktiengesellschaft (DE) 1986-04-16 EP disclosed
US-4530978-A Salt formation with an acid; cathodic electrocoating of metal BASF AKTIENGESELLSCHAFT (DE) 1985-07-23 US disclosed
US-4461880-A Surface-coating binders which contain blocked isocyanate groups and are suitable for cathodic electrocoating BASF AKTIENGESELLSCHAFT (DE) 1984-07-24 US disclosed
EP-0106128-A1 Enamel binders including blocked isocyanate groups, and their use in cathodic electrodeposition BASF Aktiengesellschaft (DE) 1984-04-25 EP disclosed
EP-0073412-A2 Paint binder containing a blocked isocyanate and its use in cathodic electrocoating BASF Aktiengesellschaft (DE) 1983-03-09 EP disclosed