SCHEMBL8607372

SCHEMBL8607372

Oc1ccccc1C(C(F)(F)F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 3/20 0.52
TSHR P16473 2/20 0.52
LMNA P02545 4/20 0.43
ALOX15 P16050 3/20 0.43
MAPT P10636 3/20 0.43
CA2 P00918 3/20 0.43
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 2/20 0.43
EGFR P00533 2/20 0.43
FYN P06241 2/20 0.43
MMP9 P14780 2/20 0.43
HPGD P15428 2/20 0.43
CA4 P22748 2/20 0.43
RECQL P46063 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29563390 0.80 ALDH1A1 (0.52) ALDH1A1TDP1TSHRLMNAALOX15
SCHEMBL584399 0.80 ALDH1A1 (0.52) ALDH1A1TDP1TSHRLMNAALOX15
SCHEMBL5407858 0.80 ALDH1A1 (0.52) ALDH1A1TDP1TSHRLMNAALOX15
SCHEMBL2096276 0.80 ALDH1A1 (0.52) ALDH1A1TDP1TSHRLMNAALOX15
SCHEMBL23202728 0.79 ALDH1A1 (0.56) ALDH1A1TDP1TSHRLMNAALOX15
SCHEMBL29492110 0.79 ALDH1A1 (0.56) ALDH1A1TDP1TSHRLMNAALOX15
SCHEMBL69460 0.79 ALDH1A1 (0.56) ALDH1A1TDP1TSHRLMNAALOX15
SCHEMBL1873962 0.78 ALDH1A1 (0.50) ALDH1A1TDP1TSHRLMNAALOX15
Hydrochloric Acid SCHEMBL29242576 0.77 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAALOX15
Potassium SCHEMBL29898272 0.77 ALDH1A1 (0.54) ALDH1A1TDP1TSHRLMNAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5846515-A Calixarene conjugate diagnostic agents for computerized tomography and method for using same MOLECULAR BIOSYSTEMS, INC. (US) 1998-12-08 US disclosed
US-5622687-A MOIETIES LINKED TO BACKBONE INCLUDE FLUORINE ATOMS, NITROXYL, METAL CHELATES AND/OR IODINE ATOMS MOLECULAR BIOSYSTEMS, INC. (US) 1997-04-22 US disclosed