SCHEMBL86076

SCHEMBL86076

O=C1CCOc2ccc3ccccc3c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.50
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
CYP1A2 P05177 1/20 0.46
GLA P06280 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SIRT1 Q96EB6 1/20 0.46
GPR84 Q9NQS5 1/20 0.44
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
DNMT1 P26358 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30873459 1.00 CYP19A1 (0.50) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL5672208 0.92 HPGD (0.44) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL5672672 0.89 CYP19A1 (0.43) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL86321 0.82 CYP19A1 (0.53) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL30019143 0.82 CYP19A1 (0.53) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL12283811 0.78 GPR84 (0.49) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL12284409 0.78 GPR84 (0.49) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL12609510 0.77 GPR84 (0.41) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL30240788 0.77 SMN1; SMN2 (0.54) CYP19A1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL4254800 0.76 CYP19A1 (0.50) CYP19A1KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112955141-A Improved methods for inducing tissue regeneration and lysis of senescent cells in mammalian cells AGEX治疗公司 2021-06-11 CN disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
EP-2682272-B1 INK JET RECORDING METHOD AND PRINTED MATERIAL FUJIFILM CORP (JP) 2015-08-26 EP disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8168263-B2 Photo-curable composition, ink composition, and inkjet recording method using the ink composition FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168263-B2 Photo-curable composition, ink composition, and inkjet recording method using the ink composition FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1461330-B1 3H-NAPHTHO[2,1-b]-PYRANE DERIVATIVES AND THEIR USE RODENSTOCK GMBH (DE) 2008-03-12 EP disclosed
US-6962670-B1 Determination of layer thickness or non-uniformity of layer thickness based on fluorophore additives EASTMAN CHEMICAL COMPANY (US) 2005-11-08 US disclosed
EP-1485369-A1 BLUE 3H-NAPHTHO- 2,1-B]-PYRAN DERIVATIVES AND USE THEREOF Rodenstock GmbH (DE) 2004-12-15 EP disclosed
EP-1461330-A1 3H-NAPHTHO 2,1-B]-PYRANE DERIVATIVES AND THE USE OF THE SAME Rodenstock GmbH (DE) 2004-09-29 EP disclosed
WO-2003080595-A1 BLUE 3H-NAPHTHO-[2,1-B]-PYRAN DERIVATIVES AND USE THEREOF RODENSTOCK GMBH (DE) 2003-10-02 WO disclosed
WO-2003055872-A1 3H-NAPHTHO[2,1-B]-PYRANE DERIVATIVES AND THE USE OF THE SAME RODENSTOCK GMBH (DE) 2003-07-10 WO disclosed
EP-1180660-A2 Determination of layer thickness or non-uniformity of layer thickness based on fluorophore additives EASTMAN CHEMICAL COMPANY (US) 2002-02-20 EP disclosed
US-5006544-A 5-hydroxytryptamine antagonist for psychological and gastrointestinal disorders; anxiolytic agents GLAXO GROUP LIMITED (GB) 1991-04-09 US disclosed
EP-0364274-A1 Imidazole derivatives GLAXO GROUP LIMITED (GB) 1990-04-18 EP disclosed