SCHEMBL86321

SCHEMBL86321

O=C1COc2ccc3ccccc3c21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.53
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 4/20 0.49
HSD17B10 Q99714 3/20 0.49
HPGD P15428 2/20 0.49
TSHR P16473 2/20 0.49
ALOX15 P16050 1/20 0.49
HTT P42858 1/20 0.49
GPR84 Q9NQS5 1/20 0.46
CYP1A2 P05177 1/20 0.45
GLA P06280 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DNMT1 P26358 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30019143 1.00 CYP19A1 (0.53) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL4254800 0.89 CYP19A1 (0.50) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL86076 0.82 CYP19A1 (0.50) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL30873459 0.82 CYP19A1 (0.50) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL27529711 0.81 KDM4E (0.39) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL11602558 0.78 ALDH1A1 (0.50) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL28622398 0.78 CYP19A1 (0.45) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL12283676 0.78 GPR84 (0.46) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL27922556 0.77 CYP19A1 (0.40) CYP19A1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL8231432 0.76 GPR84 (0.52) CYP19A1KDM4EALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5061592-A Aluminum substrate; photodimerizable material FUJI PHOTO FILM CO., LTD. (JP) 1991-10-29 US claimed
US-5061605-A IMPROVED SENSITIVITY TO LONG WAVELENGTHS FUJI PHOTO FILM CO., LTD. (JP) 1991-10-29 US claimed
US-4356255-A Photosensitive members and a process for forming patterns using the same FUJI PHOTO FILM CO., LTD. (JP) 1982-10-26 US claimed
JP-56033654-A None JP disclosed
US-12404304-B1 Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same SIERRA SCIENCES, LLC (US) 2025-09-02 US disclosed
US-20250179122-A1 Telomerase Reverse Transcriptase (TERT) Expression Enhancing Compounds and Methods for Using the Same SIERRA SCIENCES, LLC 2025-06-05 US disclosed
CN-113302226-A Hydroxyl urethane (meth) acrylate prepolymers for use in 3D printing 巴斯夫欧洲公司 2021-08-24 CN disclosed
CN-108947948-B N-aryl naphthofuranone imine compound and synthetic method thereof 湖南大学 2021-07-20 CN disclosed
CN-112638968-A Photocurable composition for 3D printing 巴斯夫欧洲公司 2021-04-09 CN disclosed
CN-112639034-A UV curable composition for 3D printing 巴斯夫欧洲公司 2021-04-09 CN disclosed
EP-2496230-B1 IRE-1 ALPHA INHIBITORS FOSUN ORINOVE PHARMATECH INC (CN) 2020-02-26 EP disclosed
EP-0410654-A2 Light- sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1991-01-30 EP disclosed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP disclosed
US-4942109-A LITHOGRAPHY, PRINTING FUJI PHOTO FILM CO., LTD. (JP) 1990-07-17 US disclosed
US-4916148-A AROMATASE INHIBITORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-10 US disclosed
EP-0333156-A2 Lithographic plate necessitating no dampening water FUJI PHOTO FILM CO., LTD. (JP) 1989-09-20 EP disclosed
EP-0316097-A1 Naphtho(2,1-b)furan derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-17 EP disclosed
US-4356255-A Photosensitive members and a process for forming patterns using the same FUJI PHOTO FILM CO., LTD. (JP) 1982-10-26 US disclosed
JP-S5633654-A PHOTOCONDUCTIVE COMPOSITION AND ELECTROPHOTOGRAPHIC SENSITIVE MATERIAL USING IT FUJI PHOTO FILM CO LTD 1981-04-04 JP disclosed
US-4224225-A PHOTOPOLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179122-A1 Telomerase Reverse Transcriptase (TERT) Expression Enhancing Compounds and Methods for Using the Same TERT, RNGTT, TERF2 CYP19A1 1765/4885KDM4E 1668/4885ALDH1A1 1015/4885
US-12404304-B1 Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same TERT, TELO2, POT1 CYP19A1 863/4885KDM4E 541/4885ALDH1A1 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.