Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200276 | 0.98 | KEAP1 (0.62) | KEAP1NFE2L2MAPK1GLATAS2R14 | |
| SCHEMBL7961836 | 0.93 | KEAP1 (0.68) | KEAP1NFE2L2MAPK1GLATAS2R14 | |
| SCHEMBL8606028 | 0.92 | CA9 (0.60) | KEAP1NFE2L2MAPK1GLATAS2R14 | |
| SCHEMBL8629867 | 0.91 | KEAP1 (0.57) | KEAP1NFE2L2MAPK1GLATAS2R14 | |
| SCHEMBL9972493 | 0.88 | KEAP1 (0.62) | KEAP1NFE2L2MAPK1GLATAS2R14 | |
| SCHEMBL8027618 | 0.88 | CNR2 (0.58) | KEAP1NFE2L2MAPK1TAS2R14CNR2 | |
| SCHEMBL22469193 | 0.87 | CNR2 (0.72) | KEAP1NFE2L2MAPK1TAS2R14CNR2 | |
| SCHEMBL5190476 | 0.85 | TAS2R14 (0.63) | KEAP1NFE2L2GLATAS2R14CNR2 | |
| SCHEMBL11796193 | 0.85 | KEAP1 (0.54) | KEAP1NFE2L2GLATAS2R14CNR2 | |
| SCHEMBL11554636 | 0.85 | KEAP1 (0.50) | KEAP1NFE2L2GLATAS2R14CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4389754-A1 | METAL-ORGANIC COORDINATION COMPOUND AND METHOD FOR PRODUCING THE SAME | beeOLED GmbH (DE) | 2024-06-26 | — | — | EP | disclosed |
| EP-0830351-A1 | PROCESS FOR PREPARING SUBSTITUTED POLYAZAMACROCYCLES | MONSANTO COMPANY (US) | 1998-03-25 | — | — | EP | disclosed |
| US-5721361-A | CONTACTING A DIAMINE OR TRIAMINE AND A DICARBOXYLIC ACID OR ESTER IN THE PRESENCE OF A BASE AND SOLVENT; COUPLING AGENT; REDUCTION; COMPLEXING WITH MANGANESE COMPOUNDS; ION EXCHANGING | THE MONSANTO COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| WO-1996040658-A1 | PROCESS FOR PREPARING SUBSTITUTED POLYAZAMACROCYCLES | MONSANTO COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4156683-A | CROWN COMPOUNDS USED AS CHELATING AGENTS | SCHERING CORPORATION (US) | 1979-05-29 | — | — | US | disclosed |
| US-3966766-A | CHELATING AGENTS | SCHERING CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |