SCHEMBL8607709

SCHEMBL8607709

CC([O])(O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP2C19 P33261 3/20 0.48
HIF1A Q16665 1/20 0.48
ALDH1A1 P00352 2/20 0.48
ALOX15 P16050 1/20 0.48
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
CYP3A4 P08684 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL971287 0.77 MAPT (0.45) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL164244 0.77 ALDH1A1 (0.52) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL8683368 0.77 ALDH1A1 (0.52) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL28216352 0.77 ALDH1A1 (0.52) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL240161 0.77 MAPK1 (0.50) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL249404 0.77 KMT2A (0.55) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL9669699 0.77 MAPK1 (0.50) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL1617443 0.77 ALDH1A1 (0.52) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL207978 0.77 MAPK1 (0.50) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL570521 0.77 ESR1 (0.56) MAPTKMT2ACYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0580121-B1 Photosensitive polyfunctional aromatic diazo compounds and photosensitive compositions using the same TOYO GOSEI KOGYO KK (JP) 1998-04-08 EP disclosed
US-5589315-A SHELF LIFE, SCREEN PRINTING TOYO GOSEI KOGYO CO., LTD. (JP) 1996-12-31 US disclosed
US-5430130-A Photosensitive polyfunctional aromatic diazo compounds useful in photosensitive compositions TOYO GOSEI KOGYO CO., LTD. (JP) 1995-07-04 US disclosed