SCHEMBL240161

SCHEMBL240161

CC([O])(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.50
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
ALDH1A1 P00352 3/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ALOX15 P16050 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
ESR1 P03372 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4066883 0.85 KMT2A (0.48) MAPK1MAPTKMT2AALDH1A1ALOX15
SCHEMBL9669699 0.81 MAPK1 (0.50) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL207978 0.81 MAPK1 (0.50) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL7647641 0.77 TSHR (0.52) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL8607709 0.77 MAPT (0.50) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL17078011 0.77 ALDH1A1 (0.52) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL6850 0.75 MAPK1 (0.50) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL927239 0.75 MAPK1 (0.50) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL18127935 0.75 MAPK1 (0.50) MAPK1MAPTKMT2ACYP2C19HIF1A
SCHEMBL6573475 0.75 MAPK1 (0.44) MAPK1MAPTKMT2ACYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4921887-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-01 US claimed
US-4734498-A 3β-succinimidoazetidinones as chiral intermediates ELI LILLY AND COMPANY (US) 1988-03-29 US claimed
CN-116075368-B Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2024-06-11 CN disclosed
WO-2024106438-A1 AMIDE COMPOUNDS OR SALTS THEREOF, BACTERICIDAL AGENTS FOR AGRICULTURE AND HORTICULTURE CONTAINING SAID COMPOUNDS, AND METHOD OF USING SAME 日本農薬株式会社 2024-05-23 WO disclosed
CN-116075368-A Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2023-05-05 CN disclosed
CN-105074635-B Conductive pattern laminate and electronic device including the same LG化学株式会社 2018-04-27 CN disclosed
CN-104600152-B The manufacture method of solar cell 东京应化工业株式会社 2018-01-05 CN disclosed
CN-107304220-A The method that a kind of \" one kettle way \" synthesizes 2,4,6- trimethylbenzoy-dipheny phosphine oxides 江苏英力科技发展有限公司 2017-10-31 CN disclosed
CN-105074635-A Conductive pattern laminate and electronic device including the same LG CHEMICAL LTD 2015-11-18 CN disclosed
US-8410267-B2 Regioselective reduction of fused pyrrolocarbazoles-5,7-diones TEVA SANTE (FR) 2013-04-02 US disclosed
CN-102385254-B Photosensitive resin composition DAXIN MATERIALS CORP 2013-03-06 CN disclosed
EP-0640034-A1 RAPID PROTOTYPE THREE-DIMENSIONAL STEREOLITHOGRAPHY SOANE TECHNOLOGIES INC. (US) 1995-03-01 EP disclosed
WO-1993020993-A1 RAPID PROTOTYPE THREE-DIMENSIONAL STEREOLITHOGRAPHY SOANE TECHNOLOGIES, INC. (US) 1993-10-28 WO disclosed
EP-0549364-A1 Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-06-30 EP disclosed
US-4921887-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-01 US disclosed
EP-0316820-A1 Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-24 EP disclosed
US-4359404-A Hydrogenation of esters using alkali doped heterogeneous Group VIII transition metal catalysts ALLIED CORPORATION (US) 1982-11-16 US disclosed
US-4346240-A Hydrogenation of esters using alkali doped heterogeneous group VIII transition metal catalysts ALLIED CORPORATION (US) 1982-08-24 US disclosed
EP-0057474-A2 Acylphosphine oxde compounds, their preparation and use BASF Aktiengesellschaft (DE) 1982-08-11 EP disclosed
EP-0036939-A1 Hydrogenation of esters using alkali doped heterogeneous group VIII transition metal catalysts ALLIED CORPORATION (US) 1981-10-07 EP disclosed