Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811181 | 0.86 | MEN1 (0.52) | EPHX1KDM4E | |
| SCHEMBL521656 | 0.84 | — | — | |
| SCHEMBL8610401 | 0.80 | — | — | |
| SCHEMBL44377 | 0.79 | EPHX1 (0.46) | EPHX1 | |
| Oxirane SCHEMBL28865425 | 0.76 | EPHX1 (0.50) | EPHX1 | |
| SCHEMBL8607807 | 0.76 | EPHX1 (0.39) | EPHX1KDM4EALDH1A1 | |
| SCHEMBL29203438 | 0.74 | EPHX1 (0.79) | EPHX1 | |
| SCHEMBL25254403 | 0.73 | EPHX1 (0.52) | EPHX1 | |
| SCHEMBL3301796 | 0.73 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL24485365 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | disclosed |