Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | METAP2 | P50579 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938970 | 0.82 | MEN1 (0.61) | KMT2AMEN1KDM4EMETAP2ALDH1A1 | |
| SCHEMBL15845269 | 0.81 | KMT2A (0.55) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL1232234 | 0.80 | KMT2A (0.66) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL15119498 | 0.79 | MEN1 (0.53) | KMT2AMEN1KDM4EMETAP2DAO | |
| SCHEMBL3112677 | 0.78 | KMT2A (0.64) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL29432255 | 0.78 | KMT2A (0.64) | KMT2AMEN1KDM4EMETAP2PLAU | |
| Methane SCHEMBL9370413 | 0.77 | KMT2A (0.62) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL30318916 | 0.77 | KMT2A (0.62) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL8755649 | 0.76 | METAP2 (0.53) | KMT2AMEN1KDM4EMETAP2PLAU | |
| Diethylamine SCHEMBL7880811 | 0.76 | MEN1 (0.56) | KMT2AMEN1KDM4EMETAP2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1970413-B1 | Silicone composition and a paper treatment agent comprising the same | SHINETSU CHEMICAL CO (JP) | 2012-03-28 | — | — | EP | disclosed |
| EP-2135899-A1 | Silicone composition and a paper treatment agent comprising the same | Shinetsu Chemical Co., Ltd. (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-1441009-B1 | Silicone composition and a paper treatment agent comprising the same | SHINETSU CHEMICAL CO (JP) | 2009-09-30 | — | — | EP | disclosed |
| US-7459213-B2 | Silicone composition and a paper treatment agent comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| EP-1970413-A1 | Silicone composition and a paper treatment agent comprising the same | Shin-Etsu Chemical Co., Ltd. (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-20080064814-A1 | SILICONE COMPOSITION AND A PAPER TREATMENT AGENT COMPRISING THE SAME | YAMAMOTO KENJI | 2008-03-13 | — | — | US | disclosed |
| US-20070032596-A1 | Silicone composition and a paper treatment agent comprising the same | YAMAMOTO KENJI | 2007-02-08 | — | — | US | disclosed |
| US-20040152825-A1 | Silicone composition and a paper treatment agent comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| EP-1441009-A1 | Silicone composition and a paper treatment agent comprising the same | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-07-28 | — | — | EP | disclosed |