Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607601 | 0.80 | HPGD (0.40) | KDM4EALDH1A1HSD17B10HTTTSHR | |
| SCHEMBL8607649 | 0.79 | LMNA (0.43) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL8109821 | 0.72 | CYP11B1 (0.47) | KDM4EALDH1A1HSD17B10HTTTSHR | |
| SCHEMBL3146682 | 0.69 | MCL1 (0.59) | KDM4EALDH1A1HSD17B10HTTTSHR | |
| SCHEMBL7867188 | 0.69 | CYP11B1 (0.47) | KDM4EALDH1A1HSD17B10HTTTSHR | |
| SCHEMBL3139456 | 0.65 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HTTTSHR | |
| SCHEMBL10001171 | 0.65 | HSD17B10 (0.54) | KDM4EALDH1A1HSD17B10HTTTSHR | |
| SCHEMBL8606823 | 0.65 | AR (0.37) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3950084 | 0.65 | TSHR (0.32) | KDM4EALDH1A1TSHRGAASMN1; SMN2 | |
| SCHEMBL3147857 | 0.64 | MAPT (0.62) | KDM4EALDH1A1HSD17B10HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |