Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606694 | 0.83 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL3950084 | 0.82 | TSHR (0.32) | HPGDSMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL8606823 | 0.82 | AR (0.37) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL8607103 | 0.81 | CTSK (0.35) | SMN1; SMN2KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL8609547 | 0.81 | HPGD (0.30) | HPGDSMN1; SMN2GAA | |
| SCHEMBL8608348 | 0.80 | KDM4E (0.39) | HPGDSMN1; SMN2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8725815 | 0.80 | HPGD (0.30) | HPGDSMN1; SMN2 | |
| SCHEMBL6557980 | 0.80 | LMNA (0.41) | ALDH1A1KMT2AGAAMAPTRAB9A | |
| SCHEMBL8953184 | 0.79 | NOTUM (0.36) | TSHRHTTKMT2AGAANPC1 | |
| SCHEMBL8891129 | 0.79 | HPGD (0.36) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496630-B1 | 2-Cyano-1,3-dione herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-07 | — | — | EP | claimed |
| EP-0496630-A1 | 2-Cyano-1,3-dione herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-07-29 | — | — | EP | claimed |
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| US-H1596-H | INSECTICIDES, MITICIDES, NEMATOSIDES AND ANTIPROTOZOA AGENTS | Rh one-Poulenc Inc. (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0496630-B1 | 2-Cyano-1,3-dione herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-07 | — | — | EP | disclosed |
| EP-0496630-A1 | 2-Cyano-1,3-dione herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-07-29 | — | — | EP | disclosed |