Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.33 |
| ▸ | PPARD | Q03181 | 8/20 | 0.33 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38826 | 0.96 | PPARG (0.35) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL39405 | 0.92 | S1PR4 (0.31) | — | |
| SCHEMBL6465928 | 0.87 | PPARG (0.34) | PPARGPPARDPPARA | |
| SCHEMBL14973487 | 0.86 | NAAA (0.36) | — | |
| SCHEMBL8581097 | 0.78 | PPARG (0.34) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL994337 | 0.77 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL39175 | 0.77 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL995960 | 0.77 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL992967 | 0.77 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL995729 | 0.77 | PPARG (0.39) | PPARGPPARDPPARAGPR84HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814692-A | PROTECTING POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-29 | — | — | US | disclosed |
| EP-0530139-B1 | Compositions containing 6-numbered N-heterocyclic compounds substituted with phosphonate groups | CIBA GEIGY AG (CH) | 1996-11-27 | — | — | EP | disclosed |