Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29487646 | 0.79 | ALDH1A1 (0.62) | KMT2AMAPTMEN1KCNH2FLT1 | |
| SCHEMBL954348 | 0.79 | ALDH1A1 (0.62) | KMT2AMAPTMEN1KCNH2FLT1 | |
| SCHEMBL8490842 | 0.78 | CYP2C19 (0.42) | ALDH1A1CTSKCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11350806 | 0.76 | MAPT (0.59) | KMT2AMAPTMEN1KCNH2ALDH1A1 | |
| SCHEMBL29403310 | 0.76 | MAPT (0.59) | KMT2AMAPTMEN1KCNH2ALDH1A1 | |
| SCHEMBL2520383 | 0.76 | MAPT (0.49) | KMT2AMAPTMEN1KCNH2FLT1 | |
| SCHEMBL31515465 | 0.76 | MAPT (0.49) | KMT2AMAPTMEN1KCNH2FLT1 | |
| SCHEMBL23292560 | 0.76 | MEN1 (0.59) | KMT2AMAPTMEN1KCNH2FLT1 | |
| SCHEMBL11331688 | 0.76 | ERCC5 (0.56) | KMT2AMAPTMEN1KCNH2FLT1 | |
| SCHEMBL8607500 | 0.75 | SMN1; SMN2 (0.42) | KMT2AMAPTMEN1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |