Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.40 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610303 | 0.84 | GRIK1 (0.41) | OPRL1OPRM1GRIA1GRIA2GRIA3 | |
| SCHEMBL8612845 | 0.82 | OPRM1 (0.39) | OPRL1OPRM1GRIA1GRIA2GRIA3 | |
| SCHEMBL8610066 | 0.80 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8608735 | 0.78 | GRIA1 (0.56) | OPRL1OPRM1GRIA1GRIA2GRIA3 | |
| SCHEMBL8611338 | 0.72 | OPRL1 (0.52) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8609291 | 0.69 | OPRL1 (0.48) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8672915 | 0.68 | GRIK1 (0.39) | OPRL1OPRM1GRIA1GRIA2GRIA3 | |
| SCHEMBL550225 | 0.68 | OPRM1 (0.60) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8612127 | 0.68 | OPRL1 (0.46) | OPRL1OPRM1GRIA1GRIA2GRIA3 | |
| SCHEMBL8721284 | 0.67 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |