Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613567 | 0.90 | ABCC9 (0.59) | ABCC9ABCB1 | |
| SCHEMBL8612374 | 0.90 | ABCB1 (0.53) | ABCC9ABCB1 | |
| SCHEMBL8611166 | 0.90 | ABCB1 (0.53) | ABCC9ABCB1 | |
| SCHEMBL8615119 | 0.90 | ABCB1 (0.53) | ABCC9ABCB1 | |
| SCHEMBL8616873 | 0.83 | ABCC9 (0.43) | ABCC9ABCB1 | |
| SCHEMBL10887243 | 0.83 | ABCC9 (0.61) | ABCC9ABCB1KDM4E | |
| SCHEMBL10887438 | 0.83 | ABCC9 (0.61) | ABCC9ABCB1KDM4E | |
| SCHEMBL9197699 | 0.81 | ABCC9 (0.53) | ABCC9ABCB1KDM4E | |
| SCHEMBL9197704 | 0.81 | ABCC9 (0.53) | ABCC9ABCB1KDM4E | |
| SCHEMBL9197710 | 0.81 | ABCC9 (0.53) | ABCC9ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | claimed |
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | disclosed |