Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.53 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611166 | 1.00 | ABCB1 (0.53) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL8615119 | 1.00 | ABCB1 (0.53) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL8609664 | 0.90 | ABCC9 (0.50) | ABCB1ABCC9 | |
| SCHEMBL8613567 | 0.90 | ABCC9 (0.59) | ABCB1ABCC9 | |
| SCHEMBL8616337 | 0.88 | ABCB1 (0.51) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9271120 | 0.88 | ABCC9 (0.51) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9429622 | 0.88 | ABCC9 (0.51) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9429629 | 0.88 | ABCC9 (0.51) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9691273 | 0.86 | ABCC9 (0.49) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL10887243 | 0.85 | ABCC9 (0.61) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | claimed |
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | disclosed |