SCHEMBL86097

SCHEMBL86097

CC(C)c1nc2ccccc2o1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
NPC1 O15118 5/20 0.48
RAB9A P51151 5/20 0.48
PSMB8 P28062 1/20 0.46
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
TP53 P04637 5/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HDAC4 P56524 1/20 0.44
ALDH1A1 P00352 3/20 0.43
PKM P14618 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HCRTR1 O43613 1/20 0.43
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2147325 0.88 MAPT (0.48) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL12396620 0.84 MAPT (0.46) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL2123396 0.84 MAPT (0.50) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL10902610 0.84 MAPT (0.46) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL8069919 0.84 MAPT (0.46) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL23342452 0.84 MAPT (0.46) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL10480315 0.84 MAPT (0.46) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL12915263 0.82 MAPT (0.47) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL9963730 0.81 RAB9A (0.47) MAPTNPC1RAB9APSMB8LMNA
SCHEMBL13767905 0.81 RAB9A (0.47) MAPTNPC1RAB9APSMB8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117757212-B Groove-shaped FRP profile and preparation method thereof 南京斯贝尔复合材料仪征有限公司 2024-06-11 CN claimed
CN-117050713-B OCA optical adhesive with high ink level difference filling capacity, adhesive tape and preparation method thereof 新纶电子材料(常州)有限公司 2024-04-05 CN claimed
CN-117757212-A Groove-shaped FRP profile and preparation method thereof 南京斯贝尔复合材料仪征有限公司 2024-03-26 CN claimed
CN-117569082-A Ageing-resistant hydrophilic non-woven fabric and preparation method thereof 扬州新科展纺织制品有限公司 2024-02-20 CN claimed
CN-117429153-A Electrolyte corrosion-resistant aluminum-plastic film and preparation method thereof 信阳华谷新材料科技有限公司 2024-01-23 CN claimed
CN-116445106-B Optical adhesive and preparation method thereof 湖南联兴光电科技有限公司 2024-01-05 CN claimed
CN-117050713-A OCA optical adhesive with high ink level difference filling capacity, adhesive tape and preparation method thereof 新纶电子材料(常州)有限公司 2023-11-14 CN claimed
CN-114933866-B Fuel cell membrane electrode packaging material and preparation method thereof 浙江葆润应用材料有限公司 2023-10-24 CN claimed
CN-116852816-A Battery cell heat insulation sheet and preparation method thereof 浙江葆润应用材料有限公司 2023-10-10 CN claimed
CN-115842132-B Lithium battery composite binder and preparation method thereof 江苏道赢科技有限公司 2023-09-22 CN claimed
CN-116445106-A Optical adhesive and preparation method thereof 湖南联兴光电科技有限公司 2023-07-18 CN claimed
CN-115565743-B Neodymium-iron-boron magnetic material and preparation method thereof 慈溪市新虹实业有限公司 2023-06-02 CN claimed
CN-115842132-A Lithium battery composite binder and preparation method thereof 江苏道赢科技有限公司 2023-03-24 CN claimed
CN-115747655-A High-strength material for fasteners and preparation method thereof 宁波擎海紧固件有限公司 2023-03-07 CN claimed
CN-115674828-A Multilayer fireproof material for battery and preparation method thereof 浙江葆润应用材料有限公司 2023-02-03 CN claimed
CN-114933866-A Fuel cell membrane electrode packaging material and preparation method thereof 浙江葆润应用材料有限公司 2022-08-23 CN claimed
CN-118812455-A Benzoxazoles Process for the preparation of compounds 中国海洋石油集团有限公司 2024-10-22 CN disclosed
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T REMIX THERAPEUTICS INC. 2024-07-18 US disclosed
US-7157462-B2 Therapeutic agents useful for treating pain EURO-CELTIQUE S.A. (LU) 2007-01-02 US disclosed
US-6635647-B2 Such as (4-(3,4-difluoro-phenyl)-piperazin-1-yl)-((4,4,8)-2-(3-(6-methoxy-pyridin-3 -yl)-2-methyl-propyl)-decahydro-isoquinolin-4-yl)-methanone; schizophrenia, depression, anxiety, bipolar disorders NOVARTIS AG (CH) 2003-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T HNRNPAB, HNRNPC, HNRNPA1 MAPT 2035/4885NPC1 459/4885RAB9A 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.