Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954548 | 0.84 | MEN1 (0.34) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL12550107 | 0.84 | KDM4E (0.39) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL34476529 | 0.82 | MEN1 (0.34) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL12572308 | 0.82 | ALDH1A1 (0.34) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL34475595 | 0.82 | MEN1 (0.34) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL8615805 | 0.80 | MEN1 (0.40) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL1951360 | 0.79 | PPM1D (0.33) | MEN1KMT2AF10POLB | |
| SCHEMBL9797061 | 0.79 | MEN1 (0.40) | ALDH1A1KDM4EMEN1KMT2AF10 | |
| SCHEMBL8607079 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL18367198 | 0.76 | TSHR (0.38) | ALDH1A1LMNACYP3A4GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849802-A | Fungicidal spirocyclic amines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |