Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12550107 | 0.86 | KDM4E (0.39) | ALDH1A1RECQLMEN1KMT2APOLB | |
| SCHEMBL1954548 | 0.86 | MEN1 (0.34) | ALDH1A1RECQLMEN1KMT2APOLB | |
| SCHEMBL34475595 | 0.85 | MEN1 (0.34) | ALDH1A1RECQLMEN1KMT2APOLB | |
| SCHEMBL34476529 | 0.85 | MEN1 (0.34) | ALDH1A1RECQLMEN1KMT2APOLB | |
| SCHEMBL8609745 | 0.82 | ALDH1A1 (0.42) | ALDH1A1RECQLMEN1KMT2APOLB | |
| SCHEMBL8615805 | 0.82 | MEN1 (0.40) | ALDH1A1MEN1KMT2APOLBF10 | |
| SCHEMBL9797061 | 0.81 | MEN1 (0.40) | ALDH1A1MEN1KMT2APOLBF10 | |
| SCHEMBL1684321 | 0.78 | OPRM1 (0.46) | MEN1KMT2APOLBSMN1; SMN2KDM4E | |
| SCHEMBL18367198 | 0.78 | TSHR (0.38) | ALDH1A1RECQLMEN1KMT2APOLB | |
| SCHEMBL19325450 | 0.77 | OPRM1 (0.47) | MEN1KMT2APOLBMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067306-A1 | CYCLOHEXANE DERIVATIVES AS INHIBITORS OF ACETYL-COA CARBOXYLASE (ACC) | NOVARTIS AG (CH) | 2011-06-09 | — | — | WO | disclosed |