Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919212 | 0.79 | TDP1 (0.50) | CYP3A4 | |
| SCHEMBL8608910 | 0.76 | LMNA (0.43) | CTSLCTSBLMNAEPHX2 | |
| SCHEMBL8607582 | 0.74 | MMP2 (0.41) | LMNA | |
| SCHEMBL7312527 | 0.71 | CYP3A4 (0.51) | CTSLCTSBCYP3A4CTSSMEN1 | |
| SCHEMBL14099873 | 0.70 | HSD17B10 (0.53) | CTSLCYP3A4LMNASMN1; SMN2ATM | |
| SCHEMBL14099876 | 0.70 | HSD17B10 (0.53) | CTSLCYP3A4LMNASMN1; SMN2ATM | |
| SCHEMBL5099842 | 0.70 | HSD17B10 (0.53) | CTSLCYP3A4LMNASMN1; SMN2ATM | |
| SCHEMBL7418225 | 0.70 | ATM (0.52) | CTSLCYP3A4LMNASMN1; SMN2ATM | |
| SCHEMBL9815930 | 0.69 | ATM (0.51) | CTSLCYP3A4LMNASMN1; SMN2ATM | |
| SCHEMBL8442391 | 0.69 | ATM (0.51) | CTSLCYP3A4LMNASMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837873-A | PROTECTED OXYDIAMINES | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | disclosed |