Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608779 | 0.90 | SLC9A1 (0.51) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8611088 | 0.88 | SLC9A1 (0.52) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8608112 | 0.86 | CA2 (0.47) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8612110 | 0.86 | CA1 (0.51) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8608333 | 0.85 | CA2 (0.46) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8609605 | 0.85 | CA2 (0.46) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8612297 | 0.83 | CA2 (0.44) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8609000 | 0.83 | CA2 (0.44) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8609467 | 0.83 | CA2 (0.44) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8608328 | 0.83 | CA2 (0.44) | CA2CA1CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |