Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658563 | 0.86 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8611852 | 0.82 | NSD2 (0.39) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL24779254 | 0.78 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8614154 | 0.77 | NSD2 (0.41) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8610248 | 0.77 | CYP1A2 (0.40) | MAPTMEN1KMT2AALDH1A1TP53 | |
| Dimethylamine SCHEMBL8615987 | 0.76 | HSP90AA1 (0.36) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL8613188 | 0.76 | HSP90AA1 (0.44) | MAPTMEN1KMT2ARAB9ATP53 | |
| SCHEMBL15657045 | 0.75 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8148398 | 0.75 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8615984 | 0.73 | RRM1 (0.41) | MAPTMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |