Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611033 | 0.84 | MAPT (0.47) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL8609119 | 0.81 | NSD2 (0.48) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL8610248 | 0.78 | CYP1A2 (0.40) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL8611852 | 0.78 | NSD2 (0.39) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL8610168 | 0.77 | MAPT (0.46) | MAPTTSHRKMT2AMEN1CYP3A4 | |
| Dimethylamine SCHEMBL8615987 | 0.77 | HSP90AA1 (0.36) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL6403846 | 0.76 | NSD2 (0.54) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL249793 | 0.75 | CYP1A2 (0.48) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL18174238 | 0.75 | POLB (0.50) | NSD2OPRM1OPRD1HKDC1CYP1A2 | |
| SCHEMBL8615638 | 0.74 | ALDH1A1 (0.40) | MAPTTSHRKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |