Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612110 | 0.88 | CA1 (0.51) | SLC9A1CYP46A1SLC6A4SLC6A3MAPT | |
| SCHEMBL8610225 | 0.86 | SLC9A1 (0.63) | SLC9A1CYP46A1MAPTPOLBALDH1A1 | |
| SCHEMBL8699627 | 0.86 | CYP46A1 (0.51) | SLC9A1CYP46A1SLC6A4SLC6A3MAPT | |
| SCHEMBL8609124 | 0.84 | SLC9A1 (0.51) | SLC9A1CYP46A1MAPTALDH1A1LMNA | |
| SCHEMBL8608779 | 0.84 | SLC9A1 (0.51) | SLC9A1CYP46A1SLC6A3MAPTCA12 | |
| SCHEMBL8610606 | 0.83 | SLC9A1 (0.50) | SLC9A1CYP46A1MAPTPOLBALDH1A1 | |
| SCHEMBL8610266 | 0.83 | SLC9A1 (0.50) | SLC9A1CYP46A1MAPTNPSR1POLB | |
| SCHEMBL8701058 | 0.81 | MAPT (0.40) | CYP46A1MAPTNPSR1ALDH1A1TSHR | |
| SCHEMBL8609093 | 0.81 | SLC9A1 (0.48) | SLC9A1CYP46A1SLC6A4SLC6A3MAPT | |
| SCHEMBL8610651 | 0.81 | SLC9A1 (0.48) | SLC9A1CYP46A1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |