Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.63 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608047 | 0.89 | PTGS2 (0.52) | SLC9A1PTGS2ALDH1A1KDM4EMAPT | |
| SCHEMBL8611088 | 0.88 | SLC9A1 (0.52) | SLC9A1CYP46A1LMNATDP1PTGS2 | |
| SCHEMBL8610220 | 0.86 | SLC9A1 (0.51) | SLC9A1CYP46A1LMNAALDH1A1CYP2C9 | |
| SCHEMBL8608779 | 0.86 | SLC9A1 (0.51) | SLC9A1CYP46A1LMNATDP1PTGS2 | |
| SCHEMBL8609124 | 0.86 | SLC9A1 (0.51) | SLC9A1CYP46A1LMNAALDH1A1CYP2C9 | |
| SCHEMBL5087619 | 0.86 | SLC9A1 (0.48) | SLC9A1CYP46A1PTGS2CYP2C9KDM4E | |
| SCHEMBL8610606 | 0.85 | SLC9A1 (0.50) | SLC9A1CYP46A1LMNAPTGS2ALDH1A1 | |
| SCHEMBL8610266 | 0.85 | SLC9A1 (0.50) | SLC9A1CYP46A1LMNATDP1PTGS2 | |
| SCHEMBL8608742 | 0.83 | SLC9A1 (0.48) | SLC9A1CYP46A1PTGS2ALDH1A1MAPT | |
| SCHEMBL8611097 | 0.83 | SLC9A1 (0.48) | SLC9A1CYP46A1LMNATDP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |