Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616215 | 0.89 | ESR1 (0.35) | — | |
| SCHEMBL10616220 | 0.81 | L3MBTL1 (0.31) | — | |
| SCHEMBL28240722 | 0.81 | ATM (0.40) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL8755602 | 0.79 | CYP2D6 (0.42) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL2343046 | 0.78 | CYP2C19 (0.40) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL5226202 | 0.78 | CYP1A2 (0.50) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL11622082 | 0.78 | MEN1 (0.46) | ATMCYP2D6OPRM1CYP2C19CYP1A2 | |
| SCHEMBL11594323 | 0.78 | CYP1A2 (0.55) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL14101166 | 0.76 | ALDH1A1 (0.38) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL31310650 | 0.75 | CYP2C19 (0.42) | CYP2D6DRD2DRD4OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477444-B1 | Carbanionic polymerisation initiators | COUNCIL SCIENT IND RES (IN) | 1998-04-08 | — | — | EP | disclosed |
| EP-0088707-A1 | 2,7-Polyalkylnaphthyridines and process for their preparation | RHONE-POULENC S.A. (FR) | 1983-09-14 | — | — | EP | disclosed |