SCHEMBL8610765

SCHEMBL8610765

Cc1cc(O)c(Cc2cc(O)c(C)cc2O)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.52
HIF1A Q16665 4/20 0.52
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
G6PD P11413 2/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 2/20 0.52
ALOX15 P16050 2/20 0.52
ALOX12 P18054 2/20 0.52
MAPK1 P28482 2/20 0.52
CYP2D6 P10635 2/20 0.52
HSD17B10 Q99714 2/20 0.52
CYP1A2 P05177 1/20 0.52
PKM P14618 1/20 0.52
CCR6 P51684 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26834212 0.91 MAPT (0.44) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL278396 0.90 ALDH1A1 (0.46) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL14181474 0.88 ALDH1A1 (0.46) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL8346860 0.88 ALDH1A1 (0.46) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL7786171 0.86 AMY1A (0.45) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL224889 0.84 ALDH1A1 (0.52) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL29713830 0.84 ALDH1A1 (0.52) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL14283799 0.84 KDM4E (0.52) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL9231605 0.82 KDM4E (0.50) MAPTHIF1AKDM4EALDH1A1CYP2C9
SCHEMBL14283762 0.82 KDM4E (0.50) MAPTHIF1AKDM4EALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10036303-A None JP disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
JP-H1036303-A NEW DIHYDROXYBENZENE DIMMER, EPOXY RESIN CURING AGENT AND EPOXY RESIN COMPOSITION NIPPON KAYAKU CO LTD 1998-02-10 JP disclosed