Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15376233 | 0.82 | HDAC1 (0.43) | SCD5GPR119TSHRALOX15ATM | |
| SCHEMBL31283885 | 0.82 | GPR119 (0.43) | MMP13GPR119TSHRALOX15ATM | |
| SCHEMBL1668225 | 0.81 | MEN1 (0.44) | GPR119TSHRALOX15ATMHDAC1 | |
| SCHEMBL3893444 | 0.79 | USP30 (0.51) | USP30SCD5GPR119TSHRALOX15 | |
| SCHEMBL8610935 | 0.79 | USP30 (0.56) | USP30SCD5GPR119TSHRALOX15 | |
| SCHEMBL240381 | 0.79 | TSHR (0.57) | USP30GPR119TSHRALOX15ATM | |
| SCHEMBL6331587 | 0.77 | MMP13 (0.41) | MMP13MMP1ACKR3USP30SCD5 | |
| SCHEMBL29891456 | 0.77 | ACKR3 (0.53) | MMP13ACKR3SCD5GPR119TSHR | |
| SCHEMBL5241257 | 0.77 | ACKR3 (0.53) | MMP13ACKR3SCD5GPR119TSHR | |
| SCHEMBL986690 | 0.77 | GPR119 (0.47) | SCD5GPR119TSHRALOX15ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712285-A | Pyrrolo-pyridine derivatives | MERCK, SHARP & DOHME, LTD. (GB) | 1998-01-27 | — | — | US | disclosed |