Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339504 | 0.96 | AVPR2 (0.43) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7338041 | 0.93 | AVPR2 (0.42) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7340296 | 0.91 | AVPR2 (0.44) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL8008232 | 0.91 | ALDH1A1 (0.47) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7340117 | 0.91 | AVPR2 (0.40) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7340110 | 0.91 | AVPR2 (0.40) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7347257 | 0.91 | AVPR2 (0.40) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7343098 | 0.90 | AVPR2 (0.41) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7345832 | 0.90 | AVPR2 (0.46) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7374548 | 0.90 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |